Alfa Laval - Pharma-line Point of Use

Pharma-line Point of Use

A compact tube-in-tube heat exchanger module developed for point of use cooling in pharmaceutical water systems. The Pharma-line Point of Use is designed to remain sanitized even when not in use (standby mode).

Pneumatic Point of Use 640x360

Efficient point of use cooling

  • Easy installation: The Pharma-line Point of Use is built as a plug-and-play module for any installation.
  • Hygienic design: Designed to eliminate risk of contamination. No internal welds, and fully drainable on the product side with no dead legs.
  • Quick response: When switching from 'stand-by mode' to 'cooling mode', cold water is available within seconds.
  • Minimized waste of water for injection & purified water due to the low hold-up volume and quick heat exchanger response
  • Minimum maintenance: The Pharma-line Point of Use is virtually maintenance free with no internal gaskets.

The Pharma-line Point of Use meets the stringent hygienic standard imposed by both control authorities and industry. With a unique design that gives high shear force and turbulence, this minimizes risk of bio-film build-up and ensures an efficient heat transfer. All product wetted parts in the Pharma-line Point of Use are electropolished and the tubes as seamless. For quick and easy installation, the Pharma-line Point of Use is supplied as a complete insulated module with a pitot tube arrangement and either manual or automatic valves. Installed in a water system, the Pharma-line Point of Use module can be regarded as a sub-loop of the main loop.

Standard sizes

The Pharma-line Point of Use is available in four standard sizes with a heat transfer area ranging from 0.3 m² to 1.0 m² , allowing a flow rate up to 1000 or 1500 l/h.

How it works


Operating principles

The Pharma-line Point of Use heat exchanger is made up of three tubes positioned concentrically within each other. The product flows in the centre channel meeting the service media in the inner and outer channel to get full countercurrent flow and thereby efficient heat transfer.

Installed as a complete point-of-use cooler the heat exchanger is kept sanitized all the time. In stand-by mode, part of the hot WFI is taken via the pitot tube for a continuous flow through the heat exchanger. Hot WFI is possible to take out through the user point. When cold WFI is needed, the cooling mode is turned on by an air switch, which closes the recirculation valve and opens the cooling water valve. Cold WFI is available within seconds and no need for flushing or draining of the system before drawing WFI or PW.



Product catalogue

Alfa Laval's hygienic equipment product catalogue "Close at hand" includes product leaflets, performance curves, links to animations, brochures and price lists for ordering purposes.

Close at hand 2019 - Cover image 640x360

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CAD portal

Download the product models in Neutral or Native CAD file formats. It is also possible to download 3D PDF files.

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Visit the animations site and take a look inside a product to see and understand how it works. 


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Heat exchangers